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  • 15 May 2025
  • Dr Boshi

📝 Mounjaro vs Wegovy: Which Weight Loss Jab Is Right for You in 2025?

If you’re considering weight loss injections in Kempston, you’re not alone. In 2025, Mounjaro and Wegovy are leading the way for those seeking medical support with weight management across the UK — but which one is right for you?

At 121 Clinic in Kempston, Bedford, we’ve received countless questions from patients wondering exactly that. This guide will help you understand the key differences, benefits, side effects, and suitability of both Mounjaro and Wegovy, so you can make a safe, confident, and informed choice.

Weight loss injections have quickly become one of the most talked-about solutions for tackling obesity and stubborn fat, and in this article, we break down everything you need to know about these two leading medications.

🔍 What Are Mounjaro and Wegovy?

Both are prescription weight loss injections designed to help reduce appetite, regulate blood sugar, and support long-term weight management. However, they work in slightly different ways:

✔️ Mounjaro (Tirzepatide)

  • Dual-action GLP-1 and GIP receptor agonist

  • Originally developed for type 2 diabetes

  • Shows stronger weight loss results than Wegovy in recent studies

  • Weekly injection

✔️ Wegovy (Semaglutide)

  • GLP-1 receptor agonist

  • First licensed weight loss jab in the UK

  • Also, indicated to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke)

  • Taken once a week

  • Proven track record and widely prescribed

📊 Mounjaro vs Wegovy: Side-by-Side Comparison

Feature Mounjaro Wegovy
Active Ingredient Tirzepatide Semaglutide
Mechanism GLP-1 + GIP dual agonist GLP-1 agonist only
Weight Loss Results 15–21% average loss 10–15% average loss
Approved In UK? Yes, limited availability Yes, widely available
Common Side Effects Nausea, constipation, fatigue Nausea, diarrhoea, headache
Ideal For? Higher BMI, insulin resistance General weight loss support

🧠 How Do These Jabs Work?

✅ Mounjaro

It mimics two hormones (GLP-1 and GIP) that regulate blood sugar and appetite. This dual action helps you feel fuller longer, reduces cravings, and supports faster fat loss.

✅ Wegovy

Acts on GLP-1 receptors in the brain to reduce hunger signals, regulates blood sugar, reduces cravings and appetite. 

⚠️ Side Effects to Consider

Both medications can cause:

  • Nausea

  • Constipation or diarrhoea

  • Fatigue

  • Headaches

Tip: Side effects often ease as your body adjusts. Working with a prescribing clinician is key to managing them safely.

🧬 Who Is Each Jab Best For?

👉 That’s a great question — since both Mounjaro and Wegovy are prescription-only medications, the best choice depends on a discussion with your doctor or weight loss specialist.

👉 Factors like insulin resistance, prediabetes or diabetes, and the amount of excess weight you’re carrying will guide the decision.

👉 Most importantly, the best medicine is the one your body can tolerate and stick with — sustainable results come from a treatment plan that fits you.

 

💡 Final Thoughts: Which Jab Is Right for You?

In 2025, both Mounjaro and Wegovy are powerful tools in the weight loss toolbox — but your unique health profile matters most.

Consulting with a specialist weight loss provider ensures your choice is safe, effective, and aligned with your body’s needs. The best jab is the one that works with your metabolism, not against it.


🎯 Ready to Find the Right Weight Loss Jab?

At 121 Clinic, we offer expert consultations to match you with the most suitable weight loss injection for your body and goals.

📞 Call or WhatsApp 07785 587032 to book your free 10-minute assessment, or join us at our Free Open Day at 121 Clinic, Kempston on 30th May to discover which weight loss option is right for you.