- 10 August 2026
- Dr Boshi
Modern Approaches and Treatments for Menopause
Menopause is a natural stage of life, but that does not mean women should simply be expected to tolerate difficult or disruptive symptoms, such as hot flushes, and sleep disturbances.
Today, our understanding of menopause has changed significantly. Modern menopause care is increasingly focused on individualised treatment, shared decision-making and addressing the whole person, rather than treating menopause as a condition that women simply have to "put up with". Start you transformation today book your consultation.
From hormone replacement therapy (HRT) and non-hormonal medicines to lifestyle interventions, nutrition and personalised weight-management strategies including microdosing, there are now more options available to help women feel well during perimenopause and menopause.
What is menopause?
Menopause is defined as the point when a woman has not had a menstrual period for 12 consecutive months, provided there is no other underlying cause.
However, the transition usually begins earlier during perimenopause, when fluctuating hormone levels can cause a wide range of symptoms.
These may include:
- Hot flushes and night sweats
- Irregular or changing periods
- Poor sleep
- Fatigue
- Brain fog and difficulty concentrating
- Anxiety or low mood
- Irritability
- Reduced libido
- Vaginal dryness
- Joint and muscle aches
- Changes in skin and hair
- Weight gain or difficulty losing weight
- Changes in body composition
Not every woman experiences the same symptoms, and their severity can vary considerably.
This is why modern menopause care should be personalised rather than one-size-fits-all.
HRT: A major part of modern menopause treatment
Hormone replacement therapy, commonly known as HRT, remains one of the most effective treatments for many menopausal symptoms.
HRT replaces hormones that the body is no longer producing at the same levels, primarily oestrogen and, when required, progesterone.
Depending on individual circumstances, HRT may be available as:
- Patches
- Gels
- Sprays
- Tablets
- Progesterone capsules
- Hormonal intrauterine systems
The choice of treatment depends on factors such as symptoms, age, whether the woman has a uterus, medical history, previous treatments and personal preferences.
For many women, transdermal oestrogen, such as patches or gel, can be an attractive option because it avoids first-pass metabolism through the liver and is associated with a lower risk of venous thromboembolism than oral oestrogen.
However, HRT is not appropriate for everyone and should be prescribed following an individual clinical assessment.
Personalised HRT rather than "one-size-fits-all" treatment
One of the most important developments in modern menopause medicine is recognising that there is no single HRT regimen that is right for every woman.
Treatment may need to be adjusted depending on:
- The woman's symptoms
- Age and stage of menopause
- Menstrual pattern
- Presence or absence of a uterus
- Previous HRT experience
- Risk factors
- Personal preferences
- Response to treatment
Follow-up is also important. A treatment that works well initially may need adjustment as symptoms and circumstances change.
The aim is not simply to prescribe hormones. The aim is to find a safe and effective treatment strategy that improves quality of life.
Vaginal symptoms deserve attention too
Vaginal dryness, discomfort during sex, urinary symptoms and recurrent urinary tract infections can become more common after menopause.
These symptoms can have a significant effect on relationships, confidence and quality of life, yet many women are reluctant to discuss them.
Local vaginal oestrogen can be an effective treatment for genitourinary symptoms of menopause and generally results in very low systemic absorption.
Other options may include vaginal moisturisers and lubricants, depending on the symptoms and individual circumstances.
Menopause care should therefore address genitourinary symptoms as well as hot flushes and night sweats.
What about women who cannot or do not want to take HRT?
HRT is not the only option.
Some women cannot take HRT because of their medical history, while others may prefer a non-hormonal approach.
Depending on the symptoms, non-hormonal strategies can include:
- Lifestyle modifications
- Cognitive behavioural therapy (CBT)
- Sleep interventions
- Certain prescription medicines
- Treatments specifically targeting vasomotor symptoms
- Vaginal moisturisers and lubricants
- Psychological and emotional support
The appropriate approach depends on the individual woman and the symptoms that are affecting her most.
Menopause, weight gain and metabolic health
Weight gain is one of the most frequently discussed concerns during perimenopause and menopause.
However, it is important to understand that menopause-related changes in weight are not simply caused by "hormones".
Ageing, reduced muscle mass, changes in activity levels, sleep disruption, appetite, stress and changes in body composition can all contribute.
Many women notice an increase in abdominal fat and a reduction in lean muscle mass.
This makes muscle preservation, resistance training, adequate protein intake, nutrition and physical activity particularly important during midlife.
For women who meet appropriate clinical criteria, medical weight-management treatments may also be considered as part of a broader personalised programme.
Importantly, weight-management treatment should not replace good nutrition, physical activity or menopause care. Instead, these approaches can sometimes work together.
Menopause and mental wellbeing
Menopause can affect emotional wellbeing as well as physical health.
Hormonal fluctuations, poor sleep and life circumstances can contribute to:
- Anxiety
- Low mood
- Irritability
- Reduced confidence
- Difficulty concentrating
- Emotional changes
A modern approach to menopause recognises that these symptoms deserve to be taken seriously.
Depending on the individual, treatment may involve HRT, psychological therapies such as CBT, lifestyle interventions, treatment of sleep problems or other appropriate medical interventions.
Persistent or severe depression or anxiety should always receive appropriate clinical assessment.
Lifestyle medicine is part of menopause care
Medication is only one part of modern menopause management.
Lifestyle interventions can have an important role in supporting health throughout midlife.
Strength training
Resistance exercise can help maintain muscle mass and support bone health.
Protein and nutrition
A balanced diet with sufficient protein, fibre, vegetables, fruit and healthy fats can support metabolic and cardiovascular health.
Sleep
Poor sleep is common during perimenopause and may be worsened by night sweats, anxiety or lifestyle factors.
Improving sleep habits and treating underlying causes can make a significant difference.
Cardiovascular health
As women age, cardiovascular risk factors become increasingly important. Blood pressure, cholesterol, blood glucose, weight and physical activity should form part of appropriate midlife health assessments.
Bone health
Oestrogen plays an important role in maintaining bone health. Menopause is therefore an important time to consider calcium and vitamin D intake, weight-bearing exercise and individual osteoporosis risk.
The future of menopause treatment
Menopause medicine continues to evolve.
The modern approach is moving away from viewing menopause simply as the absence of periods and towards a broader midlife health model.
This means considering:
Hormonal health + metabolic health + cardiovascular health + bone health + mental wellbeing + sexual health + lifestyle
Rather than asking only, "How can we stop hot flushes?", clinicians can ask:
"What does this woman need to feel healthy and function at her best during this stage of life?"
That shift is at the heart of personalised menopause care.
When should you seek medical advice?
You do not need to wait until symptoms become severe before seeking help.
Consider speaking to a healthcare professional if you are experiencing persistent symptoms such as:
- Hot flushes or night sweats
- Significant sleep problems
- Mood changes or anxiety
- Brain fog
- Reduced libido
- Vaginal or urinary symptoms
- Unexplained changes in weight or body composition
- Symptoms affecting work, relationships or quality of life
If menopause symptoms are affecting your everyday life, there are treatment options available.
Personalised menopause care
At 121 Clinic, we believe menopause care should be individualised, evidence-based and focused on the woman as a whole.
Our approach can include assessment of symptoms, discussion of HRT and non-hormonal options, lifestyle advice and personalised support based on your individual circumstances.
Menopause is a transition — not something you simply have to suffer through.
With the right information, medical support and personalised treatment plan, many women can feel healthier, more confident and more in control during midlife.
This information is for educational purposes and does not replace an individual medical assessment. HRT and other treatments should be discussed with a suitably qualified healthcare professional. Start your transformation book your consultation today